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In 2023, authorities prosecuted 86 cases, and the first quarter of 2024 saw 33 casesnearly half the total from the previous year.

The observed increase in VTA DA neuron activity (both in bursts and in firing rate) after nicotine exposure suggests that dopaminergic tone is modified in nicotine-exposed animals

This leads to strokes, heart attacks, and other heart-related problems

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All models include covariates of interest a: smooth (or ultra) as an indicator of less harmful cigarette b: terms (such as silver) as an indicator of less harmful cigarette Table 4